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I have been looking around for Vsl3 alternatives and see many that give time release, gastro resistant as a USP. One company claimed their formula of 30B cfu is worth 450B cfu as more gets lower down the GI.

That got me thinking, i need the probiotics in my pouch, why lose lots via the stomach and GI tract when I could just deliver them directly via enema, whereby all 450B cfu make it to the place they are needed.

Has anyone tried this or have thoughts as to why it would not work? I am thinking about getting an enema bulb kit via Amazon and testing this 🤔

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A few folks have posted over the years about trying this. It’s very difficult to measure efficacy of probiotics, and one person’s results could easily be random variation. I wish Bo Shen were more interested in probiotics, since he’s one of the few people who could test this properly in a clinical trial. Heck, maybe he has - negative results are very hard to get published.

I

@Scott F posted:

A few folks have posted over the years about trying this. It’s very difficult to measure efficacy of probiotics, and one person’s results could easily be random variation. I wish Bo Shen were more interested in probiotics, since he’s one of the few people who could test this properly in a clinical trial. Heck, maybe he has - negative results are very hard to get published.

Thanks Scott.
I will report back here.  Ultimately I want to see if there is an improvement and, secondly, whether I can lower the dose to maintain a level.  Using half the amount of VSL3 will save a lot of money.  It will all be subjective

I have been using warm water enemas for 6 months and it has changed everything for me. I use the enema twice a day. I had trouble emptying pouch,which means a lot of trips to bathroom. I went from 10 -12, to 4-6 trips using enemas. I am changing over today to distilled water and I am going to put a dose of probiotic in enema. I haven’t been able to take probiotics as they upset my intestines/stomach too much. It just make sense to deliver meds where they are needed. Changing to distilled water will eliminate any chlorine and other chemicals. Will report back in a few weeks on how well they work.

@Bill K posted:

I have been using warm water enemas for 6 months and it has changed everything for me. I use the enema twice a day. I had trouble emptying pouch,which means a lot of trips to bathroom. I went from 10 -12, to 4-6 trips using enemas. I am changing over today to distilled water and I am going to put a dose of probiotic in enema. I haven’t been able to take probiotics as they upset my intestines/stomach too much. It just make sense to deliver meds where they are needed. Changing to distilled water will eliminate any chlorine and other chemicals. Will report back in a few weeks on how well they work.

Hi  Bill!  What kind of probiotic will you put in the enema?  I agree that it is a good idea to use filtered and/or distilled water to avoid chemicals.  I also wonder if aloe applied via enema would have a positive effect.  I eat it sometimes for inflammation and also apply it to my skin, but I never thought about putting it in the other way.  It might be interesting!  I would only be worried about the lemon juice that most aloe gels and juices are preserved in.  Probably would be best just to get some gel straight from the plant.  Not the most convenient, though.  I look forward to hearing about your probiotic experiment.

Last edited by Sara Marie

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