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Hi all.

In my childhood, I took prednisone all the time.

Now, with new issues, I've been on a Medrol taper while the Humira kicks in.

I was to be on 2 tabs a day this week, but over the past 2 weeks, I've developed nighttime (mostly, though it can strike other times) epigastric pain. The first time it happened, it was pretty bad, and even scared me, as I've had "heartburn" before, but this was different. The first 2 times followed eating Indian food.

So the doctor has me down to one pill a day to finish out a week (did the 3 a day for a week, did 2 days of 2 pills, and he agreed the steroid is the likely culprit here).

Anyone have issues with steroids and GI/epigastric/heartburn type issues? When should I expect them to subside?

I'm on Prevacid now in the morning (started 10/31; I know they (PPIs) can take up to 4 days to "kick in"), but I'm requiring a Pepcid around dinner time, and a Tums at bedtime. And I *still* am sometimes awakened at night with this epigastric pain.

Worried I've developed a peptic ulcer, but studies actually show steroids DON'T often cause them, though I was under the impression they did.

Thoughts? Ideas? Sympathies?

Also, my stupid seton is rubbing me internally bad enough that I'm seeing my CRS on 11/10 to hopefully have him pull it. The good news is the fistula feels fine, lol.

Can't win for losing, I suppose, no rest for the weary, and all that other stuff. Luckily I had about 3 great weeks before these new, hopefully transient things, happened.
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I was on high dose prednisone for about six months before my colectomy. No epigastric pain or upper GI distress for me. But, who knows? I could have had something going on and was unaware of it. Nobody ever looked in there and I had so much other stuff going on as a distraction. Since then, I do't take more than two weeks at a time.

Hope things simmer down for you soon.

Jan Smiler
Thanks, Jan.

I'm just watching my diet, taking the meds, and hoping that weaning off the steroid helps. I took prednisone for YEARS as a kid, never had anything upset my stomach with them, or give me this effect, but I'm older now, and guess it can happen. *sigh*

Also, this darn seton just needs OUT. Why they wouldn't let me pull it is beyond me. I need a trial with it out, anyway. I think if my surgeon was available, he would have been agreeable, but since he wasn't there this week, and his colleague was (who doesn't know me), he just didn't feel comfortable telling me to pull it. My doc's nurse was like me, like, "I don't know why he wasn't agreeable to pull it..." Oh well, I'm *trying* to make it to Monday, but owie. Owie owie owie. Every time I go to the bathroom, owie. Then, I'm shoving butt cream up there to coat the sore place. I don't think it's a fissure, no blood, but it's right where the seton is laying, to the left and back of it. Wondering if over time, the plastic has "hardened" some because of the repeated stools over it (acid has to do something to it), and now it's less flexible? I mean, it's been in there for one year and seven months.


Guess I'll know more Monday. Ugh.

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