So the executive summary on my treatment history for inflammation of the Pouch and neoterminal ileum is: rotating antibiotics which slowly failed after 20 plus years, and now Remicade which after 6 years slowly failed at controlling inflammation in one area - my J Pouch inlet- leading to a stricture I have been getting dilated the last 6 months. I am meeting with my GI doc on January 20 for the express purpose of discussing a possible treatment change.
What is the "biologic du jour" these days? I think my GI is enamored with trying Entyvio as the second attempted biologic, his reason being, "totally different mechanism of action" than Remicade. Of course once I cut the umbilical cord on Remicade there is no looking back, and I have wondered what could happen if Entyvio doesn't work as well or at all. It's the proverbial dice roll that all of us who treat IBD ultimately have to make.