I am dying from ******* burn right now if that is the term and a flare up of what I believe is pouchitis along with my doctor. The flagyl was working great for about 3 months. Then I just got off it and switched to VSL3. Had an immediate flare up. Switched to both for a day. Then only back to flagyl ass both together did not seem to do anything. It helped me feel better for parts of the day but at night it has been miserable and morning. I think I will bump my Flagyl to 1500 a day or 3 pills. What do you guys think I should do?