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This happens for me semi-often. I love Prep H suppositories. They calm down the tissue closest to anus and, for me, allow the air to escape. I do this almost every night before bed and end up getting quite a lot of gas out before falling asleep...which in turn helps me sleep longer before my middle of the night bathroom break. I just make sure I put it in on my left side, wait 1-5 min and then turn on my right side. Often I get out way more gas than expected and feel that I just bought myself another hour of sleep before interruption!

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