Metformin and Crohn's or J-Pouch

I took it for a year or two, didn't have any issues, but I don't have Crohn's. My husband has been on it for a long time and also has UC, no issues with the metformin. There really isn't anything comparable to metformin, as the other drugs can cause hypoglycemia and weight gain. Metformin works differently to improve insulin resistance and does not cause weight gain. But, GI side effects are the most common ones. They usually subside over time though. Are you sure it is a Crohn's flare and not just the usual side effect of diarrhea and GI upset?

If it is just the side effect, you might be able to get past this by reducing the dose and increasing it gradually.

Jan

Thanks Jan,

That is good to know others have taken it with no ill effects to the illness. I do get flares so this could be just one of my flares or pouchitis and not have anything to do with the Metformin.

When you start a new non-IBD medication it's hare to seperate side effects of the meds from the illness itself.

KangaRoe

That's why I asked, since the side effect is also a disease symptom for you.

Are you going to try to stick it out a little longer, or ask to switch to something else.

Jan

Jan,

I am going to talk to the doctors but I will stick it out. I have been giving myself the enemas and I am already seeing improvement. After seeing your post I am pretty sure it is just one of my flares and not the Metformin.

Thanks again for your wisdom.

KangaRoe

Have J-pouch. Take Metformin....have for about three years. No effects I'm aware of.