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Enterin- I had very little luck using these enemas to treat active pouchitis. If you have moderate or worse pouchitis it's typically very difficult to retain the enemas for any significant period of time. As Scott mentioned, the therapeutic benefit likely corresponds to the user's ability to retain the enema and not have an immediate and irresistible urge to squirt right back out.

Last edited by CTBarrister

Cuffitis behaves a lot like UC. It can wax and wane on its own, it can be chronically troublesome, and it can disappear for a long time. Mesalamine isn't generally a short-term treatment that makes cuffitis go away. It's usually a long-term treatment to keep cuffitis under (hopefully) good control. Bad cuffitis can be definitively treated with pouch advancement surgery, but that is generally reserved for when medication isn't working adequately.

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