Does anyone have any knowledge or insight on the impact of full colectomy on the gut-brain axis? I presume that branch of the vagus nerve is severed and not reconnected to the pouch?
My surgeries were 21 years ago and I’ve felt a growing anxiety/depression since that time. So gradual that it is not related to the surgery itself. Possibly related to the lack of microbiome regulation? Or just standard anxiety/depression?