At last exam pouchitis (which had been getting less and less since original surgery to create my J pouch ) was three weeks ago finally totally disappeared......my gastro MD says this is the best he has seen my canal in the whole 18 years he has had me as a patient for my at one time extremely deep colitis.....my prescription to Xifaxan, a biologic with European roots has in thee years made me a happy camper even if itself warns and does contribute to some of the day to day diarrhea,,,,,,,,,,,
I’m glad the Xifaxan is doing the job. You didn’t mention its astonishing price, so I’m guessing that in your circumstances that isn’t a major issue. I don’t think I’d call it a biologic, though. It’s just a GI antibiotic, with minimal systemic absorption.
ARe you doing anything for the diarrhea? Do you actually have urgency, or just looser stools? Adding some soluble fiber (*not* at the same time as the Xifaxan) might help.
By this time the drug company Salis is giving my scrip as for free with no co-pay though it might be both Medicaid and Medicare that deletes payment...….New York has a tiered payment system with Xifaxan the highest possible (5) and doctor has to get permission from drug company and/or insurance for me to receive....Being that two 550 mg. tabs a day along with colestipol , which I have been taking since surgery 7 years ago.A lot of normal stools,watery, sludge like on occasion ...too many bathroom visits 10 to 12 a day, only sleep through entire nights sometimes, but boy o did the colostomy bag through the year or two of J pouch set up was extremely bad, not comfortable,separating from me at any time,irritation round the stome, and after the first three surgeries(removal,pouch building,hook up) had a fourth for the stoma point herniated, only they found number two and three,,from surgical drain pipe and painkiller hole, now I have oval mesh stapled in my inside skin, but ...well. I AM HEALTHY with no irritation seen during last partial sigmoscopy last month...….
I tried it for over a year and it didn't help. My insurance covered it but I believe it was something like $900 per month.
Salis has website where it lists Xifaxan along with about 8 other of the drugs they produce; each one associated with various forms of e. coli strains and you might want your doctor try a sample of your pouch for specific bacterial variations, and whether some of these other drugs could be effective against bad gut bacterial infection......
Thanks Art. I had a bunch of problems with my j-pouch so had to have it removed. It is good to see someone getting over a nasty problem.
I loved xifaxan! The best, but I got trush on my tongue and my Dr took me off after 2 1/2 years. It was down hill fast from then on.
Never will go on antibiotics again. I think it messed my flora so bad my pouchitis came back worse than ever. I almost lost my pouch.
i hope you can continue in it. I don’t mean to scare you. I really loved that drug.