I recently got the blissful new that I'm pregnant Smiler While I'm thrilled to pieces, I'm flipping out about how long I've been on flagyl and pregnant. I've got chronic pouchitis and have been rotating antibiotics since takdown - Flagyl, clindamycin and xifaxin but flagyl works the best. I was flaring right before I conceived so I went back to flagyl because it always works and have been on it for 6 weeks. It sounds like there is some disagreement on the safety of flagyl during the 1st trimester so to play it safe I've switched to clindmycin..which also worries me because it works for only a short time. So going forward, what other drugs could I take for pouchitis that are safe for pregnancy? (by the way I'm allergic to sulfa and augmentin Razzer) Can I go back on steroids? My clinic is closed so I'm going to call on Monday about this, but I'm trying hard not to freak out and need some reassurance...
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I was on prednisone for my UC throughout both pregnancies in the last trimester and sulfasalazine throughout the entire 9 months of both pregnancies and both my kids are healthy (16 and 18).

I know that within the first trimester they would really prefer you are not on meds if possible and if not, you're only on meds if the illness itself has more of a negative effect on the developing health of the fetus than the medication side effects would.

That being said, only your doctor can work with you to weigh the pros and cons of the meds you need to deal with chronic pouchitis. I also have chronic pouchitis and feel VERY ill when off my antibiotics and would be concerned about feeling this way throughout a pregnancy. I think you can come up with a safe combination (lowest dose possible) to keep both you and your baby well. Congratulations and best wishes!!

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