Have a huge ulcer in my pouch. Have been taking cipro for 2 weeks and the symptons are abating. Hopefully with exercise and diet I will be able to come off the cipro. My question is I wonder if any doctors have suggested that ulcers in the pouch is a recurrence of the original ulcerative colitis and if any doctors have suggested biologics in the treatment of pouchitis. So far, my new doctor ( my other one has retired) is making no comment. Just curious what other people have been told. Am worried that if my pouch does not clear, I may have to have it removed in the future and have the regular outside pouch, although I have been told a long time ago that this is a very extensive surgery.