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Hello All- Has anyone had any issues with arthritis/gout? I have had my Jpouch for 8 years. Doctor prescribed me Indomethacin for some relief (this spring has been the worst ever for me..all in my ankles and feet). When I looked up Indomethacin it says it IS an NSAID and can cause bowel perforation. Yikes. Anyone have any useful tips for me on how to get some relief without putting my Jpouch at risk? Thank you in advance:-) Andrea

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I had several bouts of gout about 20 years ago and my rheumatologist put me on Allopurinol.  He stated that if I maintained a uric acid level under 6 that I would never have another episode of gout.  We found that a daily dose of 400mg of Allopurinol achieved that result and that is what I still take. I have had no episodes of gout while on this medication.  This medication has had no adverse effects on my pouch. Ask your doctor about this medication.

Indomethacin killed my hubby's normal gut. Pains nearly immediately on dosing. I'd shy away from that one, if I was you. All NSAIDS have potential bowel side effects, but some truly are stronger. For instance, diclofenac induced my kid's first flare. 

 

Not to say you can't take NSAIDS with a pouch under supervision... some here do. It's just recommended to be avoided. My surgeon said they definitely increase pouchitis risks and also strictures. 

Last edited by rachelraven

Allopurinol doesn't do a darn thing for acute gout attacks. It's used to prevent attacks, and can take some time to figure out the right dose. They should be planning to measure your blood uric acid level at some point to see if 100 mg is enough.

 

The usual drug to treat acute attacks is colchicine. Colchicine causes diarrhea in coloned people, but I can't help but wonder if we're immune to that side effect. NSAIDs are usually used for pain and inflammation relief during acute attacks, but they can trouble J-pouches (and I'm allergic), so I went straight to prednisone and got good results. Now that my allopurinol dose is right (for me) I haven't had an acute attack in years.

 

Are you seeing a rheumatologist? They're more likely to know what they're doing.

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