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No harm with one caveat:

If you use NSAIDs more than occasionally (and even with occasional use, but with less caution), you need to be very aware of the risk of GI irritation and bleeding, which sometimes can be sudden and serious. If you have any bleeding or any significant GI upset associated with the use of NSAIDs, you need to stop them. You may be able to continue use with lower doses or frequencies, but maybe not. If you intend to use them regularly, it should be under a doctor's supervision, with periodic checks of your blood counts and liver function.

I used ibuprofen in high doses for years, then meloxicam, until I had to stop due to elevated liver enzymes and pouchitis. That led to getting referred to a rheumatologist and being diagnosed with enteropathic arthritis. I have since been put on Humira, and now Simponi for it, with reasonably good results. But, I have to take Norco daily for pain. I keep the dose small.

The main thing is knowledge and supervision of your doctor. The good news is that these side effects are reversible. However, there is another side effect of heart disease that may not be reversible, so if you are in a high risk group, you need to be monitored in that area too.

Jan Smiler

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