I used to take VSL3# DS just after my takedown for like a month . Then I cut it out slowly. It was great in not letting build up of excess gas and I felt good. I slowly cut it down . Now I take no meds . There is some gas but I think my pouch and intestines are slowly absorbing more and I can hold much longer. Havent had any pouchitis so far or a blockage so its pretty much the same. But yeah its a good supplement overall in digesting foods when you are bulking and when you eat big meals. Give it a try nothing's bad about the med.