Reply to "VSL#3 DS Was A Complete Fail"

Scott FMember

I'm sorry the VSL alone didn't do the trick for you, CT.

I'm not aware of any evidence that VSL helps prevent C diff. I guess it might, though, and won't do any harm. If that's your goal, though, you could add S. Boulardi as a more targeted approach. S. Boulardi would also be less controversial *during* antibiotic usage, since it's definitely not killed by the antibiotics.

CT, even though the VSL alone was insufficient to help with (or even delay onset of) pouchitis, it might be worth experimenting with using it during an antibiotic course, too. My rationale would be that (assuming it's not completely destroyed by the antibiotic) it would have more time to work. The time course you described may simply be too short for VSL to have any effect - the underlying pouchitis conditions just came roaring back immediately. Just a possibility...

7/20/1411:49 AM

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