I took 2 double strength VSL3 packets per day. Each in apple sauce or a chocolate breakfast shake due to the taste for me. That's what I could afford but should have been taking more most likely. I think it helped some and it does work for many. However, I was just too far gone and it didn't help me much. I still believe in probiotics a great deal. I took mine with antibiotics also. Good luck and I hope this helps.