Yes! For years I was so tired all the time. I had K-Pouch 30+ years and now BCIR. Anyway a doctor put me on Nascabol nasal spray once a week and prescription strength vitamin D and it changed my life. Before that I slept til noon, took a two hour nap and went to bed before nine. After starting Nascabol I started getting up before 8:00 a.m., no nap, and staying up til 10:00. I felt like a teenager again. I still do only now I’m stuck in bed by 2:00 in the afternoon because I’m in so much pain, never the less, the Nascabol is a B complex that will do the job because it doesn’t need to go through our limited digestive track.