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Vedolizumab

First, I am glad I found this forum.  I thought I was the only person out there that felt like broken glass has been going through my (insert explicit word here).  I jokingly say that, but it is the worst pain I have ever felt.  Nonetheless, a little background: UC, total colectomy J-Pouch December 1988, take down March 1989.  Pouchitis off and on over the last 29 years.  But over the past 3 years has become more severe and more frequent.  Most flare-ups I take off of work, and the last one lasted 3 weeks.  I am currently on Cipro and Flagyl.  Because of the severity and frequency, the GI doctor is now suggesting vedolizumab (taken IV).  I have done my research and for starting something like this makes me a little nervous.  Is anyone possibly taking this and can give some feedback?

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