Last month I was in the hospital for a few days to have some gall stones removed (appeared on an outpatient MRCP) and because I tested positive for c.diff. I went to the ER because I was having uncontrollable diarrhea and I knew it was something more than just Pouchitis. They gave me oral Vancomycin for the c.diff. During the ERCP to remove the stones, the doctor noted that there was no evidence of PSC. When I got out of the hospital, I kept on taking Vancomycin for a few days and noticed that my Pouchitis pretty much disappeared. My stools had a weird smell and looked a little orangey, but I'll take it!
Five days ago, I went to the ER (and was admitted 9 hours later) because I was feeling super tired, was scratching my front and back like crazy, lacked an appetite and was jaundiced. Elevated liver enzymes from blood work had them thinking it was stones again, so I had another ERCP and that's when they discovered NO STONES but PSC instead. They cleaned my sclerosed bile ducts and I was placed on some IV fluids and some Hydroxyzine for the itching. A smart PA there put me on Vancomycin as a precaution for c.diff and I noticed my Pouchitis symptoms improve to where there were no more loose or watery stools. I just got out yesterday and will continue to take Vancomycin for my Pouchitis. My new diagnosis of PSC has me a little rattled, but it looks like there are some ongoing trials for PSC treatments...one of which is Vancomycin (via the Mayo clinic): https://www.pscpartnersregistr...clinical-trials.html
Anyone else dealing with PSC?
Anyone else on prolonged use of Vancomycin for Pouchitis?