Subzero-Yikes! That sounds scary-sorry! My docs say my next steps are Humira or Remicade, with Entivyo to follow if/when those don't work. I thought I was facing surgery a few years ago. Now I just keep hoping I have enough time left on immuran and then roll through these biologics once that stops working to buy enough time for something new to come along to keep staving off surgery. I wish you the best!