I have been taking continuous antibiotics for 25 years to treat Pouch inflammation. The only side effects I ever had were minor and were due to not rotating. 10-14 days is kind of a blip on the radar compared to my 25 years, don’t you think? On the other hand I do realize that some people have severe reactions after one day. But I think if you tolerate you tolerate and if you don’t you don’t. You find out quickly.