Reply to "Research question"

John95Member

Joe,

One area of research that is of interest to me has to do with the possible damage incurred by the tight junctions connecting the epithelial cells in the intestines. If something is inhibiting or interfering with the integrity of the tight junctions (especially the claudin proteins), then perhaps the intestines are more permeable to pathogens, which then precipitates an immune response and subsequent inflammatory cascade.

As I mentioned in another post, I've suffered from eczema for many years and have noticed that dairy products exacerbate it. Given that the surface of the skin is lined with epithelial cells, perhaps there is a protein in dairy, such as casein, which is weakening the tight junctions there. I've just applied this same logic to the gut.

What are your thoughts on this?

2/18/131:05 PM

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