@Zeninu4 posted:Thanks for the explanation SteveG. I will check that out. I used to be able to get suppositories but now I was told insurance won’t cover it. I wondered if that would be less systemic. I worry that chronic use of antibiotics will cause resistant bacteria and mess up the microbiome,
I’d suggest appealing the insurance company denial of suppositories, since that’s the best way to deliver medication to a disconnected J-pouch.
There is no “normal” or “natural” microbiome in a J-pouch, since it’s not a natural space. If antibiotics make you feel better then protecting your J-pouch microbiome is the least of your concerns. To consider it another way, if your symptoms diminish or disappear on antibiotics then that’s creating a better microbiome for you than the one you develop without antibiotics.
Antibiotics can have real and consequential side effects, of course - there’s no need to create fictional ones.
Good luck!