My antibiotic usage since Entyvio has been terrible. I got to a point where I was only taking 1-2 pills a week or sometimes every 2 weeks. Was rotating between augmentin and Flagyl. The first 2 infusions of Entyvio I felt ok, (Started January of 2020) but then after that I got worse and worse with each infusion. I flared so bad that I took a 2 week course of cipro (which I hadn't touched in 5 years) which calmed my flare down but resulted in 2 bouts of c diff, which I got cleared finally in January of this year. I was doing "ok" until March then I started to get massive flare, nothing was working and then in June I started getting better, Cipro started working, then I switched to Augmentin which was working for almost a week, I felt great the day of my infusion but that night start to flare again and it's been getting worse since that day. I cannot pinpoint anything else that has changed.