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Reply to "Remicade Failed For Pouchitis/Crohn's - What's Next?"

CTBarrister, there are several options if your GI is free to choose between Crohn's and colitis treatment. It is not important how you call it, as you already said.

Entyvio is said to have few side effects and take effect in the bowel only. Adalimumab (e.g. Humira) has a similar mechanism to Remicade / infliximab, so it would be a logical continuation. But the chances to lose efficiency due to antibiodies are higher.

I've tried several of the modern meds in the past years, also Xeljanz and Stelara, but unfortunately none of them helped me.

Have you thought about leaving some space to the next therapy and trying antibiotics (again) in the meantime? You've been off antibiotics for several years now and there might be a good effect again, also with respect to your stricture.

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