One more question for those of you who may have experienced it or know... Can Remicade caused sleeplessness? It seems I have been having a tough time getting a full night's sleep lately. It may be due to other reasons or stressors I have been dealing with. It's no fun waking up at 5am after going to sleep at midnight, 1am or later and feeling tired and lacking sleep all day. I remember those Prednisone days well from back in the 90s before my surgery. Benadryl helps but makes me drowsy and it can be hard to break that cycle I find when using it as a sleep aid. Sometimes when I wake up at 4 or 5am and can't sleep, I will take one or 2 Benadryl. But it can't take an hour or more for the drowsiness to really kick in. Them I eventually fall asleep and wake up at 10 or 11 am and feel drowsy. It ends up eating up a lot of my time. Then becomes an ongoing cycle again and again.