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Reply to "Recurrent pouchitis"

C. diff is no fun, that’s for sure. Cipro can predispose you to C. diff, but Flagyl doesn’t. Flagyl is even used to treat C. diff, though it often isn’t very effective.

I first went on long-term Cipro in 2009 (approximately). I wasn’t able to find any other antibiotics that worked, including Flagyl, so I unfortunately couldn’t rotate antibiotics. Cipro alone did the trick for about 5 years, and then began to lose effectiveness. Surprisingly, adding Flagyl worked like a charm, and the combination has continued to work for me very nicely. I’ve worked hard to find the lowest effective doses of each medication to minimize side effects.

If the antibiotic combination stops working then I’ll probably start on a biologic medication. What’s important to me is that I live my life like a healthy person, without the bathroom exerting power over me.

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