Sorry, I haven't been checking the site for awhile and just saw your message. I start with 3 capsules after meals twice a day, and then after a week cut back to 2 caps twice a day for 3 more weeks. Then 1 cap twice a day for another month or two. (My naturopath does things very cautiously). In the beginning the Mycostat would cause me to burp and had an odd smell, but either the burping went away or I got used to the smell, because it didn't seem so bad after awhile.