Probiotics likely won’t do your health any harm, and it’s possible that they could help, but the best of them will put a big dent in your bank account. My (high dose) probiotics retail for over $600 per month; once my annual out-of-pocket maximum is met my insurance company pays for them, but I wouldn’t do it if my body hadn’t made it clear that pouchitis is much more than hypothetical for me. Some people do well with lower doses, and many people do just fine with none.