Reply to "Probiotics - how much?"

Johnny, this is a difficult topic.  There's no point in having a strong probiotic of it never reaches the gut.  A strain of probiotic is probally the same between brands, the difference between the expensive and cheap brands trends to be the delivery method.

 

Basically, you need a buffer mixed into you probiotic so it didn't get destroyed in your stomach (many do).  And you need the buffer not to be so effective that the probiotic didn't activate in the gut, otherwise it passed right through.. 

 

To complicate matters further, our anatomy is slightly non standard which affects transit times too.

 

This is why VSL (which is dry frozen btw) is the only probiotic that's been tested to work for pouches. It cost then a lot of money to prove the delivery method was just right for pouches.  I've never used vsl3, so I'm not giving you a sales pitch  I provided links to research in previous posts on this site, which shows 2 or 3 products reach the gut, but others don't (note this is normal gut not j-pouch, and only a handful of products were tested)  from this research I decided to use a liquid based probiotic which was proven to reach the gut (again the research was not done on j-pouch) but at least I know it gets there which is half the battle lol.

 

What I'm saying is, if your comparing probiotic based on strength, your missing the point... Don't fall for the sales patter xxx billion.. look for some evidence that it actually colonises the gut.  If there's no evidence, then it's likely never been tested, so how do you know it works?  It's complicated to get delivery right.  Dry frozen is perhaps the most stable form (liquid needs to be kept chilled etc) but harder to deliver because it had to activate at the right time to colonise the gut.  So not only does it have to survive the stomach, but then activate in the pouch for long enough to colonise.  Liquid solutions are already active, so if it survives the stomach it stands a better chance of colonising.  I'm afraid you need to make a decision on a product either on people's testimonials (which is tricky at best), or documentary proof from the company itself.

 

As an example, I took a dried frozen version of a popular probiotic for years without considering this.  In the study I referenced earlier which compared several products, the version I had been taking didn't reach the gut in any significant volume in any test!  They concluded that single strain yoghurts were actually more effective than my probiotic.  

 

By all means try the products you found, but if it doesn't work out could just be a bad product rather than the probiotics not working for you.

 

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