Rotate antibiotics (try augmentin, tinidazole, and xifaxin, rotate every 2 weeks), take Pepto Bismol at least 2 hours before or after antibiotic dosages, reduce sugar/carbs in your diet, and try that for a while. If you are not progressing with antibiotics, biologics is the next level of treatment. I was on rotating antibiotics to treat pouchitis for over 20 years, and the pouchitis was kept in a "simmering" state. But eventually it progressed over time, and I had to go on Remicade. I am doing better on Remicade than I ever was on antibiotics, and I am now off antibiotics completely. Good luck.