Reply to "Omeprazole/Prilosec"

Scott FMember

I'm on a double dose of Prilosec for LPR (it's like "silent GERD"). I have no side effects and have never had C. Dif. Ease off any PPI very slowly - there tends to be an acid rebound effect that can be miserable. A couple of years ago I actually failed one attempt to get off Nexium, and damaged my teeth (with the acid reflux) in the process. My second attempt worked better, but required a taper that made prednisone look easy - I added about an hour to the dosing interval each day. In retrospect I'd be aggressive with Zantac during a PPI withdrawal, since Zantac is easier to stop.

6/9/133:21 PM

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