Had my takedown 2 months ago (April 13), and been going to the bathroom constantly. Started on lomotil (2 tabs four times a day) which wasn't working, so started on Tincture of opium on Tuesday night. First 24 hours were my best 24 hours since surgery, so was very hopeful, but last 48 have reverted back and last night - Friday - was a nightmare with leakage (leakage is actually a polite word for what happened). So now worried that nothing is working. Can the opium take time to get working or does this mean it's not working? And if it's not, what then? I know 2 months out is not that long, but if meds are doing nothing to help, should I be worried that this pouch thing isn't going to work for me? This was all the result of rectal cancer, and had neoadjuvant radiation and chemo - would that raise my chances of the pouch not taking? Beginning to worry.