Although I never developed AVN, I also remain traumatized by prednisone. For me that translates into being *more* receptive to biologics, mainly as a way to reduce/eliminate any potential need for prednisone. Body parts (including the immune system) can malfunction over time. FWIW, as time passes and our systems age we’re all likely to need maintenance therapy for an increasing number of things. I’m glad you had such a long run of good health without medication.