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Reply to "Mast Cell Activation Disorder, Histamine Intolerance and Chronic Pouchitis"

Interesting side note. The "sulfa" abx I took that "caused" my colitis:  sulfamethoxazole and trimethoprim could have indeed caused a massive mast cell cascade that flipped the switch on: "sulfonamide antimicrobials interact with the MRGPRX2 receptor and trigger a mast cell response." 

If anyone else here had a sudden onset after taking a sulfa drug, holler :-0

Ref article: "Typical antimicrobials induce mast cell degranulation and anaphylactoid reactions via MRGPRX2 and its murine homologue MRGPRB2"



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