I haven't been on this site for awhile. Doing well and living life!
I have been rotating antibiotics for 8 years (few months after I got my j-pouch). I had issues early on with yeast infections and a general itchiness and always needed probiotics. But I think my body just learned to adjust to the antibiotics, and I no longer have that side effect nor need probiotics. Cipro doesn't work great for me anymore since I was on it for 6 straight months for pouchitis prescribed by my surgeon who didn't seem to understand the importance of rotating. I was then on Augmentin low dose for 15 months (pregnancy and nursing) since it was the best and really only good option during that time. So, Augmentin doesn't work well for me anymore either. I also was on Pepto for about a year, which worked great, but also, no longer effective. Now, I'm very good about rotating. I rotate through Flagyl, Xifaxan, and Alinia. I will throw in Cipro and Augmentin in once in awhile, but they aren't as effective.
Additionally, I take a very LOW DOSE of antibiotics. I'm sure all of them would still work and work well if I upped my dose. I just take one tablet at bedtime, which does the trick.
Also, I have to be careful with Flagyl. I have had issues with tingling fingers and toes, which I assume was neuropathy. It's happened multiple times and stops within a day of me getting off the Flagyl. But, it works the best for me still of all the antibiotics so I generally give it several months break and go back to it again and see how I do.