Here’s another possibility. I’ve had pouchitis or cuffitis symptoms ever since takedown 2 years ago. Two weeks ago, I had a pouchoscopy and was told I have chronic cuff inflammation plus a new one: my pouch was said to be “angulated” and “flapping in the breeze.” My GI said he even had trouble scoping the top part of the pouch because it had folded over. He concluded that my frequency symptoms and nighttime leakage might be happening because of this angulation. I am now scheduled for a barium enema so the pouch position can be visualized. If a folded pouch is the reason for my symptoms, the doc said it could mean another surgery to tack the pouch in place.