Eczema can sometimes behave like that. Mine is limited to my left hand, and aggressive use of neutral, unscented hand cream has kept it at bay for about a year. SInce steroid cream can’t penetrate the palm very well, I’m glad the hand cream is working. I think the hand cream is better at preventing an outbreak than treating it, which makes it harder to apply to your situation. And I don’t know if yours is eczema.