I’m assuming nothing. I expect brand-name drugs to get unreasonable price increases for the next few years - they are trying to establish outrageous baseline prices in case price controls take the form of controls over price increases. The combination product is overpriced hocus-pocus, and the two generics (loperamide and simethicone) might be much cheaper. The best way to express dissatisfaction with the price is to stop paying it. Thank goodness there are alternatives.