I used tincture of opium that was prescribed by my doctor while I was going through cancer treatment after 15 years of well-controlled UC with good old sulfasalazine, that made my pee like sunshine. It was well controlled for most of that time, but not at first, and I think the scar tissue that formed when I was first sick became the cancer, but who knows? Maybe it was the long term use of the sulfa drugs that caused the cancer? Or just random chance. At any rate, I would NOT recommend tincture of opium to slow down the guts. There are too many side effects to use it regularly enough for what is most likely needed. I was an emotional basket case because of the constant rollercoaster ride of being blissed out right after taking my tincture and then the come down before the next dose. In my opinion, recreational use of opium on occasion is A-OK, but for any sort of consistent therapy, it's not the road to healing. Also, I'd say it's totally OK if death is imminent.