It has been over a year and I am doing better on the Simponi than Humira, although I wound up injecting every 3 weeks instead of monthly at first, but now am back to monthly. My inflammatory markers are way down and my GI said my pouch/rectal cuff never looked better. My rheumy says they just keep making better and better biologics. Simponi just completed phase 3 clinical trials for UC, so FDA approval is just around the corner. I was surprised that they did trials for UC before Crohn's on this one.
Jan
