Actually this is what killed Elvis Presley, straining on the toilet from constipation due to his addiction to prescription pain killers. He was found keeled over in front of the toilet seat, pants around ankles, dead. First of all, do not abuse pain killers. Second, if you do get constipation from taking bowel slowers, counteract it with natural laxatives, or reduce the bowel slowers. Last, don't strain. Not only may it cause a fatal cardiac event, but even if you have a healthy heart, you may still get a nasty case of hemorrhoids.