I had to go back to a ostomy for uncontrolled pouchitis i was told to give it a year and then go from there well immediately after I developed diversion colitis and after a consult with my surgeon a second opinion with another GI and my GI I started on Entyvio Between the second and third loading dose I reversed and have been doing great now over 2 1/2 years later For me Entyvio worked immediately I had my ostomy for 4 months before I started Entyvio and was reversed a month later good luck I almost lost my pouch of 18 years