Scott, I have not tried eliminating the probiotic. I have been taking it for years without this problem, so I doubt that is a cause, plus I take it with my supper. I would imagine a day's dose would wear off by 2:00 the following day. The more I think about it, the more I think it is stress-related. I am taking Anatomy & Physiology, for crying out loud. According to my classmates, they try to fail people in this course.