Thanks for responding CTB23. VSL#3 hasn't closed its doors, it's the company that I was getting it from that closed it's doors. I just can't afford the medication. I will try something else, and I will look. Thank you for responding to my inquiry. I'm sorry MEMA 1 that you're having such a hard time. I hope you will be able to get your problem under control. I remember when I first got my j-pouch, I was afraid to move for fear that I would have to use the restroom.....when my rear end was soooo very sore. I use to live on Imodium AM 24-7, so I know your pain. But do try the Imodium because it works. Please try to calm down and stop thinking the worse. Stop eating at about 6:30 pm so you can get a good nights sleep and make sure to use the Imodium it will help you. That way your trips to the restroom will be very limited. You may have to adjust the time you have your last meal of the day until you get your situation under control.