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Reply to "Have continued to have cramping and strong urge to go, still going on 3 years"

Neither of those drugs alone did anything for me. Cipro, on the other hand, was a nearly immediate miracle. When an antibiotic isn't helping with pouchitis after a few weeks something needs to be changed - either the dose or the medication. Multiple years of an antibiotic that isn't helping is just wildly inappropriate.

Another thing that sometimes helps in chronic pouchitis is significant doses of a good probiotic. I have had good results with VSL #3 DS (I'm at 4 packets/day).

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