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Reply to "Flagyl/Metronidazole dosage"

For chronic pouchitis requiring long-term antibiotic therapy it’s pretty straightforward to find the lowest effective dose, as CT describes. This doesn’t work as well with acute pouchitis, since lowering the dose too much can prolong the treatment and increase the likelihood of resistant organisms flourishing. You really don’t want symptoms redeveloping in the middle of a 10-14 day course of treatment. It’s not an exact science, but it can be guided by whatever worked (and was well tolerated) the previous time.

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