Well many people are on a daily dose of antibiotics. I have used Flagyl in the past but it makes everything I eat have a funny taste to it so i switched to Cipro. Cipro seems to work better for me actually. Any medicine has a side effect you have to weight the benefits from the risk. Your ligaments can bother you will you stay on a higher dosage of cipro. If I have a problem I usually just take cipro for a couple days and stop. Only one 500 mg pill. If it gets really bad then I start with 2 - 500 a day for ten days. My pouch will settle down after just one day with Cipro it seems to work better for me.