Hi - I tried Humira and Remicade and Entyvio and Stelara. Entyvio and Stelara are both pretty safe and for me I had zero side effects. I would try Entyvio first - it targets the gut directly and I believe it is achieving better results for IBD. Entyvio is harder to administer because it is IV only - but painless. Neither worked wonders for me, but I would not be too worried about taking either of them.