I've had chronic cuffitis and pouchitis and had been on cipro and flagyl rotating for 7years and as soon as I stopped talking them I would get sick so decided to try Entyvio infusions and have been on it for a year and it took the whole year for it to work and finally in remission but just last week I started with the stomach cramps and urgency and now I think I have pouchitis or cuffitis I can't tell the difference. They both hurt just as much. I have no side effects from Entyvio.